6-Chloro-2,4-Dinitroaniline
A heavily deactivated dinitro-chloroaniline building block supplied by Chelora Chemicals for dye, pigment and fine-chemical synthesis — exported from Indonesia in technical and high-purity grades, with full batch documentation on every shipment.
What 6-Chloro-2,4-Dinitroaniline is, and why buyers source it
A working overview of the compound's chemistry, its place as one of the most heavily deactivated diazo-component building blocks we supply, and the grades Chelora Chemicals keeps in regular supply.
6-Chloro-2,4-Dinitroaniline carries a chlorine and two nitro groups arranged around a single amino group — the most heavily substituted member of the chloronitroaniline family we supply. With two strongly electron-withdrawing nitro groups and a chlorine all acting on the same ring, the amino nitrogen is pulled far toward non-basic behaviour: this is a very weak base, and converting it to a diazonium salt requires the most forcing acid conditions of any compound in our chloronitroaniline range.
At room temperature it is a yellow crystalline solid, reported in the literature to exist in three distinguishable polymorphic (crystal) forms that differ in mechanical handling properties, though all represent the same chemical substance. It is only sparingly soluble in water, dissolving more readily in polar organic solvents such as acetone and DMF.
Where it fits in the synthesis chain
Despite its low basicity, this compound is used industrially as a diazo component for certain azoic and pigment chemistries where the extra nitro group shifts the coupled product's shade and lightfastness relative to the mono-nitro chloroanilines in our range. It is also used more broadly as a dinitroaromatic building block in fine-chemical synthesis.
Grades we supply
Chelora Chemicals offers 6-Chloro-2,4-Dinitroaniline in technical grade (≈97% assay) for standard industrial synthesis, and high-purity grade (98%+) for applications sensitive to isomer carryover or polymorphic form. Both grades are supplied with a batch-wise certificate of analysis so your incoming QC team can verify the parameters you ordered against.
How 6-Chloro-2,4-Dinitroaniline is made
An overview of the production route for orientation purposes. Our manufacturing partners' own process parameters and in-process controls are proprietary and are not disclosed beyond what is needed to interpret the certificate of analysis.
6-Chloro-2,4-Dinitroaniline is manufactured from 1-chloro-2,4-dinitrobenzene by ammonolysis: the chlorine on that starting material is strongly activated toward nucleophilic aromatic substitution by the two flanking nitro groups (ortho and para to it), so reaction with ammonia under moderate pressure and temperature cleanly displaces the chlorine actually targeted for displacement and installs the amino group in a different ring position, leaving one chlorine and both nitro groups on the product.
Because 1-chloro-2,4-dinitrobenzene itself carries two chlorine-activating nitro groups, careful stoichiometric and temperature control is needed during ammonolysis to react at the intended position selectively and avoid over-substitution or the formation of related positional by-products.
After ammonolysis, the crude product is washed, recrystallized and dried to remove unreacted starting material, regiochemical by-products and ammonium salts before packing. This recrystallization step is also where the product's dominant polymorphic form is typically set.
Why this is among the more specialized grades we carry
With two nitro groups and a chlorine on the ring, there are several structurally similar chloro-dinitroaniline isomers that could form under slightly different reaction conditions. We qualify our manufacturing partners on regiochemical consistency for this specific grade, since buyers sourcing it for a defined dye or pigment shade need the exact substitution pattern reported on the certificate of analysis, not a close positional relative.
Industries and processes that use it
6-Chloro-2,4-Dinitroaniline is consumed as a specialized diazo-component and dinitroaromatic building block. The fields below account for most of the global demand we see through our export desk.
Azoic Dyes & Pigments
A diazo component for certain azoic dye and pigment shades, diazotized under strongly acidic conditions and coupled with a naphthol partner to build the colourant's chromophore.
Dinitroaromatic Fine-Chemical Synthesis
Used as a building block for further dinitroaromatic intermediates in fine-chemical and process research, where the chlorine remains available for substitution chemistry.
Pharmaceutical Intermediates
Supplied in smaller volumes as a specialized building block for pharmaceutical synthesis routes that call for this dinitro-chloroaniline scaffold.
Specialty Chemical Research
Used in materials and specialty-chemical research exploring the properties of polysubstituted nitroaromatic amines, including their polymorphic behaviour.
How the molecule is typically carried forward
Two nitro groups make this the most deactivated amine in our chloronitroaniline range; the remaining ring chlorine, activated by the same nitro groups, is often the more reactive site.
Diazotization (Diazo Component Use)
Under the most forcing acid conditions used for this class of weakly basic amine, the amino group is converted to a diazonium salt for azoic dye and pigment coupling.
Azo Coupling
The diazonium salt is coupled with a naphthol AS-type coupler to form the azo (–N=N–) chromophore for the finished colourant.
Nucleophilic Aromatic Substitution at Chlorine
The remaining ring chlorine, strongly activated by the two nitro groups, is readily displaced by amine, alkoxide or thiolate nucleophiles under mild conditions — often the more practical reactive handle on this molecule than the deactivated amine.
Nitro Group Reduction (Selective or Full)
Controlled catalytic or chemical reduction can target one or both nitro groups, giving mono- or diamino products used as further dye and fine-chemical intermediates.
6-Chloro-2,4-Dinitroaniline against other chloronitroanilines we supply
Buyers sourcing this heavily deactivated diazo component often need a related mono-nitro chloroaniline for comparison or a neighbouring shade. A quick reference to what else is on our regular supply list.
| Product | CAS Number | Category | Notes |
|---|---|---|---|
| 6-Chloro-2,4-Dinitroaniline | 3531-19-9 | Mono-chloro di-nitro primary arylamine | The product on this page — our most heavily substituted, most deactivated chloronitroaniline. |
| 2,5-Dichloro-4-Nitroaniline | 6627-34-5 | Dichloro mono-nitro primary arylamine | A less-deactivated dichlorinated diazo component — see its product page. |
| 2,6-Dichloro-4-Nitroaniline | 99-30-9 | Dichloro mono-nitro primary arylamine | Also supplied as the Dichloran fungicide active — see its product page. |
| Ortho Chloro Para Nitro Aniline | 121-87-9 | Mono-chloro mono-nitro primary arylamine | Our least-substituted, most reactive diazo component — see its product page. |
Exact physical constants and purity specifications are confirmed per batch on the certificate of analysis — treat the notes above as a sourcing guide, not a specification sheet, for products other than 6-Chloro-2,4-Dinitroaniline.
Safety classification at a glance
Based on GHS classification as commonly listed for this substance. This is a summary for orientation only — always work from the current safety data sheet supplied with your specific batch.
Fatal if swallowed (Acute Tox. 2 Oral).
Fatal in contact with skin (Acute Tox. 1 Dermal).
Fatal if inhaled (Acute Tox. 2 Inhalation).
Causes skin irritation and serious eye irritation.
May cause respiratory irritation.
May cause damage to organs through prolonged or repeated exposure (STOT RE 2).
Toxic to aquatic life, with long-lasting effects.
Danger — among the more severe classifications in our chloronitroaniline range; GHS06 toxic and GHS08 health hazard pictograms apply.
This is one of the more acutely hazardous grades in our chloronitroaniline range, with Acute Tox. 1 (dermal) and Acute Tox. 2 (oral, inhalation) classifications. Use impervious gloves, full eye/face protection and respiratory protection sized to the task; avoid any skin contact and work under local exhaust ventilation. Full first-aid, storage, spill and PPE guidance is in the MSDS issued with every shipment, and should be read in full before this material is handled.
Keeping it on spec between delivery and use
General storage guidance for this grade. Site-specific storage rules, segregation requirements and re-test intervals should follow your own EHS procedures and the MSDS issued with your batch.
Store in a dry, well-ventilated area out of direct sunlight, in tightly closed original packaging, segregated from strong oxidizing and reducing materials. As a polysubstituted nitroaromatic compound, bulk quantities should be stored away from heat sources and shock per standard nitroaromatic handling practice, even though this material is not classified as an explosive. If a batch is held past its retest date, re-check assay and colour before it goes into a process.
How it ships from Indonesia
Standard packing and export terms for this product. Confirm exact figures against your order — they vary slightly by destination and quantity.
What travels with every batch
Specification is agreed before the purchase order, not discovered on arrival. Every shipment of 6-Chloro-2,4-Dinitroaniline leaves with a documented, checkable paper trail.
Certificate of Analysis
Batch-wise assay (by HPLC/GC), melting point range, colour and moisture, issued against the agreed specification so your QC team can check it, not just file it.
Safety Data Sheet
GHS-format SDS in English covering hazard classification, handling, storage, first-aid and spill response for the exact grade shipped.
Technical Data Sheet
Reference physical and chemical properties, recommended storage and typical applications, for internal circulation to your process or R&D teams.
Certificate of Origin
Confirms Indonesian origin for customs clearance and any preferential-duty claim at your destination port.
Dangerous Goods Declaration
UN packing group, classification and shipper's declaration prepared ahead of loading so documentation never holds up customs.
Third-Party Inspection
Independent pre-shipment inspection and re-sampling can be arranged on request, at your cost, for buyers who require it as a matter of policy.
Frequently asked questions
What buyers most often ask our sales desk about this grade.
01What is 6-Chloro-2,4-Dinitroaniline used for?+
02What is the CAS number of 6-Chloro-2,4-Dinitroaniline?+
03Why is this compound less basic than the other chloronitroanilines you sell?+
04What purity grades does Chelora Chemicals supply?+
05Is 6-Chloro-2,4-Dinitroaniline hazardous?+
06What packing options are available?+
07How long does delivery take?+
08Can I get a sample before placing a bulk order?+
09Do you supply other chloronitroanilines?+
10How is 6-Chloro-2,4-Dinitroaniline manufactured?+
Need 6-Chloro-2,4-Dinitroaniline on spec, on time?
Send us your required purity, quantity, packing preference and destination port. Our desk quotes most enquiries within one working day.