Diisopropylamine

Diisopropylamine (DIPA) carries two isopropyl groups on a secondary amine nitrogen, and is formed industrially as the co-product of a larger reaction aimed primarily at making isopropylamine. We want to flag two genuine data points we found in tension rather than average them away: first, reported flash points for this compound range from −6 °C to −17 °C across the sources we checked (likely reflecting open-cup vs. closed-cup test methods), and we show that as a range rather than a single falsely precise number; second, reported water solubility ranges from a specific "10 g/L, slightly soluble" figure to a flat "miscible," a genuine discrepancy between sources that we flag rather than silently resolve — check the SDS for your specific lot if this matters for your process.

Its documented commercial uses are as an intermediate in the synthesis of several herbicide and pesticide active ingredients, and as a corrosion-inhibitor and rubber-chemical intermediate, consistent across supplier technical literature we reviewed, though we were not able to independently verify specific named end products beyond this general level.

Where it fits in the synthesis chain

We supply Diisopropylamine itself as a pesticide/herbicide and rubber-chemical intermediate. We do not manufacture or supply the finished agrochemical or rubber products made from it.

Grades we supply

99%+ technical grade is the standard commercial offering.

Diisopropylamine is formed as the secondary-amine co-product of isopropylamine manufacture, via reductive amination (hydrogenative amination) of acetone with ammonia and hydrogen over a metal catalyst.

Reaction conditions and the ammonia:acetone ratio determine the split between the primary product (isopropylamine) and this secondary-amine co-product; the two are separated by distillation after the reaction.

The crude diisopropylamine fraction is purified by further distillation and tested for purity and colour before packing, since it is sold as a distinct commercial product in its own right rather than only as an incidental by-product stream.

A real discrepancy between EU and Japanese hazard classifications

We want to state this plainly rather than pick the more convenient figure. The EU's harmonised CLP Annex VI entry (Index 612-129-00-5) classifies this compound as Flam. Liq. 2 (H225), Acute Tox. 4 across all three exposure routes (H302/H312/H332), and Skin Corr. 1B (H314) — signal word Danger. Japan's NITE classification, an independent government classification body, is genuinely stricter on several points: Acute Tox. 3 by inhalation (H331, not the EU's Category 4/H332), Eye Dam. 1 (H318), and STOT SE 1 for the respiratory organs (H370) — categories the EU's harmonised entry does not carry. We show the EU harmonised entry as the governing classification since it is the formally binding one for EU-facing trade, but we flag the Japanese classification's additional severity rather than omit it.