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Primary Aliphatic Amine · CAS 107-10-8

n-Propylamine

CH3(CH2)2NH2 Molar mass 59.11 g/mol

The straight-chain primary propylamine supplied by Chelora Chemicals — a building block for pharmaceutical, rubber and agrochemical intermediate chemistry wherever a small, linear primary amine is required — exported from Indonesia with full batch documentation on every shipment.

Identification Sheet REP.
IUPAC namePropan-1-amine
CAS number107-10-8
Molecular formulaCH₃(CH₂)₂NH₂
Molar mass59.11 g/mol
AppearanceColourless, volatile liquid
Common synonymsn-Propylamine, 1-Propanamine, Propan-1-amine
Melting Point–83 °Clit.
Boiling Point47 – 51 °Cat 1 atm
Specific Gravity0.719at 20 °C
Flash Point–37 °Cclosed cup, approx.
AppearanceColourless, volatile liquidammonia-like odour
Purity Offered99% / 99.5%+technical & high-purity
01 / PRODUCT DOSSIER

What n-Propylamine is, and why buyers source it

A working overview of the compound's chemistry, its place as the straight-chain isomer of the propylamines, and the grades Chelora Chemicals keeps in regular supply.

n-Propylamine is a primary aliphatic amine with an unbranched three-carbon chain: a small, reasonably basic, strongly nucleophilic amine typical of the lower straight-chain alkylamines. It readily forms amides, imines, sulfonamides and ureas, and is a competent nucleophile in substitution chemistry on activated aromatic and aliphatic electrophiles.

At room temperature it is a colourless, highly volatile, flammable liquid with a sharp ammonia-like odour, miscible with water and most organic solvents. It is handled with the same solvent-class precautions typical of low-boiling aliphatic amines.

Where it fits in the synthesis chain

n-Propylamine is used as a building block across pharmaceutical intermediate synthesis, rubber-chemical intermediate chemistry, and agrochemical intermediate manufacture wherever a small, linear, unbranched primary amine is specifically required rather than its branched isomer, isopropylamine. It is also used in general organic synthesis for amide, sulfonamide and urea formation, and in some surfactant and corrosion-inhibitor formulation chemistry.

Grades we supply

Chelora Chemicals offers n-Propylamine in technical grade (≈99% assay) for standard industrial synthesis, and high-purity grade (99.5%+) for pharmaceutical-intermediate applications sensitive to colour and water content. Both grades are supplied with a batch-wise certificate of analysis.

02 / MANUFACTURING ROUTE

How n-Propylamine is made

An overview of the production route for orientation purposes. Our manufacturing partners' own process parameters and in-process controls are proprietary and are not disclosed beyond what is needed to interpret the certificate of analysis.

n-Propylamine is manufactured industrially by catalytic amination of n-propanol with ammonia over a metal catalyst at elevated temperature and pressure, in a reaction directly analogous to the routes used for ethylamine and butylamine: CH₃(CH₂)₂OH + NH₃ → CH₃(CH₂)₂NH₂ + H₂O. An alternative laboratory-scale route proceeds by reacting 1-propanol with ammonium chloride at high temperature and pressure using a Lewis acid catalyst such as ferric chloride. Reductive amination of propionaldehyde with ammonia and hydrogen over a metal catalyst is also used in some production schemes.

Why the catalytic amination route is favoured at scale

Direct catalytic amination of the alcohol is continuous and scalable, giving good conversion with straightforward downstream distillation to separate the target amine from residual alcohol, ammonia and secondary/tertiary amine by-products.

03 / APPLICATIONS

Industries and processes that use it

n-Propylamine is consumed by pharmaceutical, rubber and agrochemical intermediate manufacture wherever a small, linear primary amine is specifically required. The fields below account for most of the demand we see through our export desk.

Field 01

Pharmaceutical Intermediate Chemistry

A building block in pharmaceutical intermediate synthesis wherever a small, unbranched primary amine is required.

Field 02

Rubber-Chemical Intermediate Chemistry

Incorporated into rubber-chemical intermediate synthesis as a linear aliphatic amine building block.

Field 03

Agrochemical Intermediate Chemistry

Used as a building block in some agrochemical intermediate synthesis routes that specifically require the linear propylamine isomer.

Field 04

General Amide & Urea Synthesis

Used broadly in organic synthesis for amide, sulfonamide and urea formation across fine-chemical manufacture.

04 / REACTION CHEMISTRY

How the molecule is typically carried forward

The primary amine's nucleophilicity and linear chain shape govern almost all of this molecule's further reaction chemistry. Reaction classes below account for most of the ways n-Propylamine is converted into a finished intermediate.

Amide / Urea Formation

Reacts with acid chlorides, isocyanates and anhydrides to give the corresponding amide or urea, a routine step in pharmaceutical and agrochemical intermediate synthesis.

Sulfonamide Formation

Reacts with sulfonyl chlorides to give the corresponding sulfonamide, used in some pharmaceutical intermediate sequences.

Nucleophilic Substitution

Displaces suitable leaving groups on activated aliphatic or aromatic electrophiles, introducing the n-propylamino group directly.

Reductive Amination Chemistry

Condenses with aldehydes and ketones to give imines that are reduced to secondary amines, used in some fine-chemical sequences.

05 / RELATED BUILDING BLOCKS

n-Propylamine against its branched isomer and other amines we supply

Buyers sourcing n-propylamine often need to confirm they want the linear isomer rather than isopropylamine for their process. A quick reference to what else is on our regular supply list.

ProductCAS NumberCategoryNotes
n-Propylamine107-10-8Primary linear amineThe product on this page — the unbranched propylamine isomer in our range.
Isopropylamine75-31-0Primary branched amineThe branched isomer, widely used in glyphosate and atrazine herbicide chemistry — see its product page.
Ethylamine75-04-7Primary ethylamineA related shorter-chain primary amine elsewhere in our range — see its product page.
n-Butylamine109-73-9Primary linear amineThe next homologue up the linear-chain series — see its product page.

Exact physical constants and purity specifications are confirmed per batch on the certificate of analysis — treat the notes above as a sourcing guide, not a specification sheet, for products other than n-Propylamine.

06 / HAZARD & HANDLING

Safety classification at a glance

Based on GHS classification as commonly listed for this substance. This is a summary for orientation only — always work from the current safety data sheet supplied with your specific batch.

H225

Highly flammable liquid and vapour.

H302

Harmful if swallowed.

H311

Toxic in contact with skin.

H314

Causes severe skin burns and eye damage.

H331

Toxic if inhaled.

PPE Standard

Impervious gloves, chemical splash goggles or a face shield, and suitable respiratory protection are the baseline for routine handling.

Ignition Sources

Highly flammable; keep away from open flames, sparks, static discharge and other ignition sources, and bond/ground containers during transfer.

Signal word

Danger — GHS02 flammable, GHS05 corrosive and GHS06 toxic pictograms apply.

This compound is a highly flammable, corrosive liquid that is toxic in contact with skin or if inhaled, causes severe skin burns and eye damage, and is harmful if swallowed. It must be handled with impervious gloves, splash-proof eye protection and suitable respiratory protection in a well-ventilated area, kept away from all ignition sources. Full first-aid, storage, spill and PPE guidance is in the MSDS issued with every shipment, and should be read in full before this material is handled.

07 / STORAGE & SHELF LIFE

Keeping it on spec between delivery and use

General storage guidance for this grade. Site-specific storage rules, segregation requirements and re-test intervals should follow your own EHS procedures and the MSDS issued with your batch.

Storage TemperatureCool, ambient
ContainerSealed drums / ISO tank
Typical Shelf Life24 months, unopened
Keep Away FromOpen flames, oxidizers, strong acids
Beyond Shelf LifeRe-assay before use

Store in a cool, dry, well-ventilated area away from direct sunlight, open flames and other ignition sources, in tightly closed original packaging, segregated from strong oxidizing agents and strong acids. If a batch is held past its retest date, re-check assay, colour and water content before use.

08 / PACKING & EXPORT

How it ships from Indonesia

Standard packing and export terms for this product. Confirm exact figures against your order — they vary slightly by destination and quantity.

Standard Packing200 kg drums
Bulk PackingIBC / ISO tank
Min. OrderFrom 1 drum
Lead Time2 – 3 weeks
Export TermsFOB · CFR · CIF
09 / QUALITY & DOCUMENTATION

What travels with every batch

Specification is agreed before the purchase order, not discovered on arrival. Every shipment of n-Propylamine leaves with a documented, checkable paper trail.

Doc 01

Certificate of Analysis

Batch-wise assay (by GC), colour and water content, issued against the agreed specification so your QC team can check it, not just file it.

Doc 02

Safety Data Sheet

GHS-format SDS in English covering hazard classification, handling, storage, first-aid and spill response for the exact grade shipped.

Doc 03

Technical Data Sheet

Reference physical and chemical properties, recommended storage and typical applications, for internal circulation to your process or R&D teams.

Doc 04

Certificate of Origin

Confirms Indonesian origin for customs clearance and any preferential-duty claim at your destination port.

Doc 05

Dangerous Goods Declaration

UN packing group, classification and shipper's declaration prepared ahead of loading so documentation never holds up customs.

Doc 06

Third-Party Inspection

Independent pre-shipment inspection and re-sampling can be arranged on request, at your cost, for buyers who require it as a matter of policy.

10 / FAQ

Frequently asked questions

What buyers most often ask our sales desk about this grade.

01What is n-Propylamine used for?+
It is a building block across pharmaceutical, rubber and agrochemical intermediate chemistry wherever a small, linear primary amine is specifically required, and is used broadly in amide, sulfonamide and urea synthesis.
02What is the CAS number of n-Propylamine?+
Its CAS Registry Number is 107-10-8, with molecular formula CH₃(CH₂)₂NH₂ and a molar mass of 59.11 g/mol.
03How is n-Propylamine made?+
Industrially by catalytic amination of n-propanol with ammonia over a metal catalyst, analogous to the routes used for ethylamine and butylamine.
04What purity grades does Chelora Chemicals supply?+
We supply technical grade (around 99% assay) for standard industrial synthesis, and high-purity grade (99.5%+) for pharmaceutical-intermediate applications. Each batch ships with a certificate of analysis.
05Is n-Propylamine hazardous?+
Yes. It is a highly flammable, corrosive liquid that is toxic in contact with skin or if inhaled, and causes severe skin burns and eye damage. It must be handled with the PPE and precautions specified in the MSDS supplied with each shipment.
06What is the difference between n-Propylamine and Isopropylamine?+
They are structural isomers: n-propylamine has the amine on a straight three-carbon chain, while isopropylamine has it on the central carbon of a branched chain. The two have different reactivity and are not interchangeable in processes that specify one isomer.
07What packing options are available?+
Standard packing is 200 kg drums, with IBC or ISO tank shipment available for bulk orders.
08How long does delivery take?+
Typical lead time is two to three weeks plus transit, depending on whether the grade is ex-stock or made to order and your destination port. A firm date is confirmed in the written quotation.
09Can I get a sample before placing a bulk order?+
Yes. Pre-shipment samples and a batch certificate of analysis can be arranged so your QC team can verify the specification before committing to volume.
10Do you supply Isopropylamine as well?+
Yes, we also supply Isopropylamine, the branched isomer of this product, widely used in glyphosate and atrazine herbicide intermediate chemistry.
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