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Primary Aliphatic Amine · CAS 109-73-9

n-Butylamine

CH3(CH2)3NH2 Molar mass 73.14 g/mol

The straight-chain primary butylamine supplied by Chelora Chemicals — a precursor to the benzimidazole fungicide benomyl and a building block across rubber, pharmaceutical and emulsifier chemistry — exported from Indonesia with full batch documentation on every shipment.

Identification Sheet REP.
IUPAC nameButan-1-amine
CAS number109-73-9
Molecular formulaCH₃(CH₂)₃NH₂
Molar mass73.14 g/mol
AppearanceColourless liquid, yellows on storage in air
Common synonymsn-Butylamine, 1-Butanamine, Butan-1-amine
Melting Point–49 °Clit.
Boiling Point77 – 79 °Cat 1 atm
Specific Gravity0.740at 20 °C
Flash Point–12 °Cclosed cup, approx.
AppearanceColourless liquidfishy, ammonia-like odour; yellows on storage
Purity Offered99% / 99.5%+technical & high-purity
01 / PRODUCT DOSSIER

What n-Butylamine is, and why buyers source it

A working overview of the compound's chemistry, its place as the straight-chain isomer of the four butylamines, and the grades Chelora Chemicals keeps in regular supply.

n-Butylamine is a primary aliphatic amine with an unbranched four-carbon chain — one of four structurally distinct butylamine isomers (alongside isobutylamine, sec-butylamine and tert-butylamine), each with its own established industrial role despite sharing the same molecular formula and molar mass. As a primary amine it is a strong nucleophile and a moderately strong base, readily forming amides, carbamates, ureas and imines.

At room temperature it is a colourless, flammable liquid with a fishy, ammonia-like odour that gradually yellows on prolonged storage in air. It is miscible with water and most organic solvents and is handled with the solvent-class precautions typical of low-boiling aliphatic amines.

Where it fits in the synthesis chain

n-Butylamine's best-documented specialty application is as a precursor in the synthesis of the systemic benzimidazole fungicide benomyl, where it is converted via n-butyl isocyanate into the carbamate side-chain of the molecule. Beyond this, it is used broadly as an intermediate for pesticides, pharmaceuticals (including the sulfonylurea drug tolbutamide and the drug fengabine) and emulsifiers, as a precursor for a rubber vulcanisation accelerator, and as a nylon plasticiser intermediate.

Grades we supply

Chelora Chemicals offers n-Butylamine in technical grade (≈99% assay) for standard industrial synthesis, and high-purity grade (99.5%+) for pharmaceutical-intermediate applications sensitive to colour and water content. Both grades are supplied with a batch-wise certificate of analysis.

02 / MANUFACTURING ROUTE

How n-Butylamine is made

An overview of the production route for orientation purposes. Our manufacturing partners' own process parameters and in-process controls are proprietary and are not disclosed beyond what is needed to interpret the certificate of analysis.

n-Butylamine is manufactured industrially by reacting n-butanol with ammonia over an alumina catalyst at elevated temperature and pressure: CH₃(CH₂)₃OH + NH₃ → CH₃(CH₂)₃NH₂ + H₂O. Reductive amination of n-butyraldehyde with ammonia and hydrogen over a metal catalyst is also used in some production schemes. The crude amine is separated from residual alcohol, ammonia and secondary/tertiary amine by-products by distillation before packing.

Why the catalytic amination route is favoured at scale

Direct catalytic amination of n-butanol over alumina is continuous and scalable, giving good conversion with straightforward downstream distillation — the same general process family used across the lower primary aliphatic amines in this range.

03 / APPLICATIONS

Industries and processes that use it

n-Butylamine is consumed by fungicide, rubber, pharmaceutical and emulsifier manufacture. The fields below account for most of the demand we see through our export desk.

Field 01

Benomyl Fungicide Precursor

Converted via n-butyl isocyanate into the carbamate side-chain of benomyl, a systemic benzimidazole fungicide used in agriculture.

Field 02

Pharmaceutical Intermediate Chemistry

A building block in the synthesis of drugs including the sulfonylurea tolbutamide and the drug fengabine.

Field 03

Rubber-Chemical & Nylon Plasticiser Intermediate

A precursor for a rubber vulcanisation accelerator and for a nylon plasticiser intermediate.

Field 04

Emulsifier Intermediate Chemistry

Used as a building block in emulsifier synthesis across several specialty-chemical formulation routes.

04 / REACTION CHEMISTRY

How the molecule is typically carried forward

The primary amine's nucleophilicity governs almost all of this molecule's further reaction chemistry. Reaction classes below account for most of the ways n-Butylamine is converted into a finished intermediate.

Isocyanate / Carbamate Formation

Conversion to n-butyl isocyanate, followed by reaction with a benzimidazole-carbamate intermediate, installs the carbamate side-chain of benomyl.

Amide / Sulfonylurea Formation

Reacts with acid chlorides and sulfonyl isocyanates to give amides and sulfonylureas, used in pharmaceutical intermediate synthesis such as tolbutamide.

N-Alkylation

Serves as the nucleophile in N-alkylation chemistry used in rubber-chemical and nylon plasticiser intermediate routes.

Reductive Amination Chemistry

Condenses with aldehydes and ketones to give imines that are reduced to secondary amines, used in some fine-chemical sequences.

05 / RELATED BUILDING BLOCKS

n-Butylamine against its other butylamine isomers we supply

Buyers sourcing n-butylamine often need to confirm it against one of its branched isomers, each with its own established industrial role. A quick reference to all four in our regular supply list.

ProductCAS NumberCategoryNotes
n-Butylamine109-73-9Primary linear amineThe product on this page — the unbranched butylamine isomer, used in benomyl fungicide chemistry.
Isobutylamine78-81-9Primary branched amineA branched isomer used in rubber and pharmaceutical intermediate chemistry — see its product page.
sec-Butylamine13952-84-6Secondary-carbon amineThe isomer used directly as a citrus postharvest fungicide — see its product page.
tert-Butylamine75-64-9Primary branched amineThe isomer used in rubber accelerator and triazine herbicide chemistry — see its product page.

Exact physical constants and purity specifications are confirmed per batch on the certificate of analysis — treat the notes above as a sourcing guide, not a specification sheet, for products other than n-Butylamine.

06 / HAZARD & HANDLING

Safety classification at a glance

Based on GHS classification as commonly listed for this substance. This is a summary for orientation only — always work from the current safety data sheet supplied with your specific batch.

H225

Highly flammable liquid and vapour.

H302

Harmful if swallowed.

H312

Harmful in contact with skin.

H314

Causes severe skin burns and eye damage.

H332

Harmful if inhaled.

PPE Standard

Impervious gloves, chemical splash goggles or a face shield, and suitable respiratory protection are the baseline for routine handling.

Ignition Sources

Highly flammable; keep away from open flames, sparks, static discharge and other ignition sources, and bond/ground containers during transfer.

Signal word

Danger — GHS02 flammable, GHS05 corrosive and GHS07 harmful pictograms apply.

This compound is a highly flammable, corrosive liquid; it causes severe skin burns and eye damage, and is harmful if swallowed, in contact with skin or if inhaled. It must be handled with impervious gloves, splash-proof eye protection and suitable respiratory protection in a well-ventilated area, kept away from all ignition sources. Full first-aid, storage, spill and PPE guidance is in the MSDS issued with every shipment, and should be read in full before this material is handled.

07 / STORAGE & SHELF LIFE

Keeping it on spec between delivery and use

General storage guidance for this grade. Site-specific storage rules, segregation requirements and re-test intervals should follow your own EHS procedures and the MSDS issued with your batch.

Storage TemperatureCool, ambient, dark
ContainerSealed drums / ISO tank
Typical Shelf Life24 months, unopened
Keep Away FromOpen flames, oxidizers, strong acids, prolonged air exposure
Beyond Shelf LifeRe-assay before use

Store in a cool, dry, dark, well-ventilated area away from open flames and other ignition sources, in tightly closed original packaging, segregated from strong oxidizing agents and strong acids. Minimise air exposure to limit the colour-forming oxidation that develops on prolonged storage. If a batch is held past its retest date, re-check assay, colour and water content before use.

08 / PACKING & EXPORT

How it ships from Indonesia

Standard packing and export terms for this product. Confirm exact figures against your order — they vary slightly by destination and quantity.

Standard Packing200 kg drums
Bulk PackingIBC / ISO tank
Min. OrderFrom 1 drum
Lead Time2 – 3 weeks
Export TermsFOB · CFR · CIF
09 / QUALITY & DOCUMENTATION

What travels with every batch

Specification is agreed before the purchase order, not discovered on arrival. Every shipment of n-Butylamine leaves with a documented, checkable paper trail.

Doc 01

Certificate of Analysis

Batch-wise assay (by GC), colour and water content, issued against the agreed specification so your QC team can check it, not just file it.

Doc 02

Safety Data Sheet

GHS-format SDS in English covering hazard classification, handling, storage, first-aid and spill response for the exact grade shipped.

Doc 03

Technical Data Sheet

Reference physical and chemical properties, recommended storage and typical applications, for internal circulation to your process or R&D teams.

Doc 04

Certificate of Origin

Confirms Indonesian origin for customs clearance and any preferential-duty claim at your destination port.

Doc 05

Dangerous Goods Declaration

UN packing group, classification and shipper's declaration prepared ahead of loading so documentation never holds up customs.

Doc 06

Third-Party Inspection

Independent pre-shipment inspection and re-sampling can be arranged on request, at your cost, for buyers who require it as a matter of policy.

10 / FAQ

Frequently asked questions

What buyers most often ask our sales desk about this grade.

01What is n-Butylamine used for?+
As a precursor to the benzimidazole fungicide benomyl via n-butyl isocyanate; also pharmaceutical intermediate synthesis (tolbutamide, fengabine), a rubber-accelerator precursor, a nylon plasticiser intermediate, and emulsifier chemistry.
02What is the CAS number of n-Butylamine?+
Its CAS Registry Number is 109-73-9, with molecular formula CH₃(CH₂)₃NH₂ and a molar mass of 73.14 g/mol.
03How is n-Butylamine made?+
By reacting n-butanol with ammonia over an alumina catalyst, or by reductive amination of n-butyraldehyde.
04What purity grades does Chelora Chemicals supply?+
We supply technical grade (around 99% assay) for standard industrial synthesis, and high-purity grade (99.5%+) for pharmaceutical-intermediate applications. Each batch ships with a certificate of analysis.
05Is n-Butylamine hazardous?+
Yes. It is a highly flammable, corrosive liquid causing severe skin burns and eye damage, and is harmful if swallowed, on skin contact or if inhaled. It must be handled with the PPE and precautions specified in the MSDS supplied with each shipment.
06How many butylamine isomers are there, and how do they differ?+
Four: n-butylamine (straight chain), isobutylamine and sec-butylamine (each branched differently) and tert-butylamine (amine on a fully substituted carbon). Each has a distinct industrial role and the four are not interchangeable.
07What packing options are available?+
Standard packing is 200 kg drums, with IBC or ISO tank shipment available for bulk orders.
08How long does delivery take?+
Typical lead time is two to three weeks plus transit, depending on whether the grade is ex-stock or made to order and your destination port. A firm date is confirmed in the written quotation.
09Can I get a sample before placing a bulk order?+
Yes. Pre-shipment samples and a batch certificate of analysis can be arranged so your QC team can verify the specification before committing to volume.
10Do you supply the other butylamine isomers as well?+
Yes, we also supply Isobutylamine, sec-Butylamine and tert-Butylamine, the other three structural isomers.
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