Di-n-Butylamine
Di-n-Butylamine is a documented carbosulfan/agrochemical and rubber-vulcanisation-chemical intermediate carrying a hazard classification currently in a genuine, documented state of transition -- we state the EU's legally current entry plainly while flagging a 2021 regulatory committee opinion to substantially tighten it, which we could not confirm has yet been formally adopted.
What Di-n-Butylamine is, and why buyers source it
A working overview of the compound's chemistry, its place in the aniline-derivative family, and the grades Chelora Chemicals keeps in regular supply.
Di-n-Butylamine carries two n-butyl groups on a secondary amine nitrogen. We want to flag something specific and important about its hazard classification rather than present one settled number: the EU's current harmonised CLP Annex VI entry (Index 612-049-00-0) classifies it at a comparatively modest Flam. Liq. 3 (H226) and Acute Tox. 4 (H302/H312/H332) tier, signal word Warning. However, we located an ECHA Risk Assessment Committee (RAC) background document showing RAC adopted an opinion in June 2021 proposing a substantially stricter reclassification — Acute Tox. 3 (H301/H311/H331, "toxic"), Acute Tox. 2 by inhalation (H330, "fatal if inhaled"), Skin Corr. 1B (H314), and Eye Dam. 1 (H318), signal word Danger. We could not confirm, as of our most recent check, whether the European Commission has since formally adopted this stricter entry into Annex VI. We state the currently binding entry as the one in force while flagging the pending, more severe proposal plainly rather than silently applying either the old or the new classification.
Commercially, it is documented by a primary manufacturer source as an intermediate for the agrochemical carbosulfan and other agrochemicals, for rubber vulcanisation chemicals (dithiocarbamate/thiuram-type accelerators), for dibutylethanolamine used in coatings, and as a precursor to tetrabutylurea used in hydrogen-peroxide processes. More general secondary sources additionally document flotation-reagent, dyestuff-intermediate, corrosion-inhibitor, and emulsifier/insecticide-intermediate uses.
Where it fits in the synthesis chain
We supply Di-n-Butylamine itself as an agrochemical and rubber-chemical intermediate. We do not manufacture or supply carbosulfan, finished rubber-vulcanisation chemicals, or any other downstream product made using it.
Grades we supply
99%+ technical grade is the standard commercial offering.
How Di-n-Butylamine is made
An overview of the production route for orientation purposes. Our manufacturing partners' own process parameters and in-process controls are proprietary and are not disclosed beyond what is needed to interpret the certificate of analysis.
Di-n-Butylamine is made industrially by catalytic reaction of ammonia with n-butanol over an alumina or silica catalyst at elevated temperature (approximately 300–500 °C) and pressure, with continuous distillation/extraction used to separate the mono-, di-, and tri-butylamine co-products.
An alternative documented route passes ammonia, n-butanol, and hydrogen over a dehydrogenation catalyst; laboratory-scale alkylation of ammonia with butyl halide is chemically straightforward but is not the industrial-scale route.
The crude di-butylamine fraction is purified by distillation, separated from the mono- and tri-butylamine co-products, and tested for purity and colour before packing.
A classification currently in transition -- flagged, not settled
We want to be precise rather than simplify this. The EU's harmonised Annex VI entry currently in force classifies this compound at Warning-tier severity. A June 2021 ECHA RAC opinion proposes a materially stricter reclassification to Danger-tier, including a doubling of acute-toxicity severity and new corrosive/eye-damage statements. As of our most recent check we could not confirm whether this proposal has been formally adopted into binding EU law. We show the currently binding, Warning-tier entry as this page's governing classification, and flag the pending proposal honestly rather than quietly adopt either the older or the newer figure as settled fact — we recommend checking ECHA's current C&L Inventory before relying on a specific classification for compliance purposes.
Industries and processes that use it
Di-n-Butylamine is consumed almost entirely as a synthesis intermediate. The four fields below account for most of the demand we see through our export desk.
Carbosulfan & Agrochemical Intermediate
Documented by a primary manufacturer source as an intermediate for the agrochemical carbosulfan and other agrochemicals.
Rubber Vulcanisation-Chemical Intermediate
Used as an intermediate in rubber vulcanisation chemicals, including dithiocarbamate/thiuram-type accelerators.
Coatings & Peroxide-Process Intermediate
A documented precursor to dibutylethanolamine (used in coatings) and to tetrabutylurea (used in hydrogen-peroxide processes).
How the molecule is typically carried forward
Di-n-Butylamine's chemistry centres on its basic secondary amine nitrogen, reactive toward the electrophiles used to build agrochemical and rubber-chemical intermediate structures.
N-Functionalisation (agrochemical/rubber-chemical chains)
The secondary amine reacts with appropriate electrophiles to build carbosulfan and dithiocarbamate/thiuram-type rubber-accelerator structures.
N-Hydroxyethylation
Reaction with ethylene oxide gives dibutylethanolamine, a documented coatings-industry intermediate.
Di-n-Butylamine against its near relatives
Di-n-Butylamine and Diisopropylamine are the two secondary alkylamines in this part of our range.
| Product | CAS Number | Typically Used In | Notes |
|---|---|---|---|
| Di-n-Butylamine | 111-92-2 | Agrochemical and rubber-chemical intermediate | The product on this page. |
| Diisopropylamine | 108-18-9 | Herbicide/pesticide intermediate; corrosion inhibitor | Also supplied -- see its product page. |
Exact physical constants and purity specifications are confirmed per batch on the certificate of analysis — treat the notes above as a sourcing guide rather than a specification sheet.
Safety classification at a glance
Based on GHS classification as commonly listed for this substance. This is a summary for orientation only — always work from the current safety data sheet supplied with your specific batch.
Flammable liquid and vapour.
Harmful if swallowed.
Harmful in contact with skin.
Harmful if inhaled.
Warning
Di-n-Butylamine's currently binding EU harmonised CLP Annex VI entry (Index 612-049-00-0) classifies it as Flam. Liq. 3 (H226) and Acute Tox. 4 oral/dermal/inhalation (H302/H312/H332) -- signal word Warning. We located an ECHA RAC opinion (adopted June 2021) proposing a substantially stricter reclassification -- Acute Tox. 3 (H301/H311/H331), Acute Tox. 2 inhalation (H330), Skin Corr. 1B (H314), Eye Dam. 1 (H318), signal word Danger -- which some REACH-registrant self-classification data already reflects. We could not confirm whether this stricter entry has been formally adopted into binding EU law as of our most recent check; the Warning-tier entry above is shown as currently governing, and we recommend verifying the live ECHA C&L Inventory before relying on a specific classification for compliance purposes. IARC has not evaluated this substance. UN transport: UN 2248, Class 8, Subsidiary risk 3, Packing Group II.
Keeping it on spec between delivery and use
General storage guidance for this grade. Site-specific storage rules, segregation requirements and re-test intervals should follow your own EHS procedures and the MSDS issued with your batch.
Store in a cool, well-ventilated area away from ignition sources and strong oxidisers, consistent with a flammable liquid with a hazard classification currently under regulatory review toward a stricter, corrosive-tier profile. We recommend handling with corrosive-liquid-level PPE as a precaution given the pending reclassification.
How it ships from Indonesia
Standard packing and export terms for this product. Confirm exact figures against your order — they vary slightly by destination and quantity.
What travels with every batch
Specification is agreed before the purchase order, not discovered on arrival. Every shipment of Di-n-Butylamine leaves with a documented, checkable paper trail.
Certificate of Analysis
Batch-wise assay (by GC), isomer purity, melting point range and moisture, issued against the agreed specification so your QC team can check it, not just file it.
Safety Data Sheet
GHS-format SDS in English covering hazard classification, handling, storage, first-aid and spill response for the exact grade shipped.
Technical Data Sheet
Reference physical and chemical properties, recommended storage and typical applications, for internal circulation to your process or R&D teams.
Certificate of Origin
Confirms Indonesian origin for customs clearance and any preferential-duty claim at your destination port.
Dangerous Goods Declaration
UN packing group, classification and shipper's declaration prepared ahead of loading so documentation never holds up customs.
Third-Party Inspection
Independent pre-shipment inspection and re-sampling can be arranged on request, at your cost, for buyers who require it as a matter of policy.
Frequently asked questions
What buyers most often ask our sales desk about this grade.
01What is Di-n-Butylamine used for?+
02What is the CAS number of Di-n-Butylamine?+
03What purity grades does Chelora Chemicals supply?+
04Is Di-n-Butylamine hazardous?+
05Is this compound classified as corrosive?+
06Does this compound have an established workplace exposure limit?+
07What packing options are available?+
08How long does delivery take?+
09Can I get a sample before placing a bulk order?+
10How is Di-n-Butylamine manufactured?+
11What is the shelf life, and how should it be stored?+
Need Di-n-Butylamine on spec, on time?
Send us your required purity, quantity, packing preference and destination port. Our desk quotes most enquiries within one working day.